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Article

Discrete gene loci regulate neurodegeneration, lymphocyte infiltration, and major histocompatibility complex class II expression in the CNS.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 29 Oct 2003

Lidman Olle, Swanberg Maria, Horvath Linn, Broman Karl W, Olsson Tomas, Piehl Fredrik

Abstract excerpt

Neurodegeneration and inflammation are fundamental aspects of many neurological diseases. A genome-wide scan of the response to ventral root avulsion (VRA) in a rat F2 cross discloses specific gene regions that regulate these processes. Two gene loci displayed linkage to neurodegeneration and T c...

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Identifiers

PMID: 14586010
PMCID: PMC6740878

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14586010-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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