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Article

HLA-B*5701 typing: evaluation of an allele-specific polymerase chain reaction melting assay.

Tissue antigens - 1 Jul 2007

Hammond E, Mamotte C, Nolan D, Mallal S

Abstract excerpt

Inheritance of HLA-B*5701 is a strong predictor of a hypersensitivity reaction to the anti-HIV drug abacavir. The identification of susceptible individuals prior to the institution of abacavir therapy is therefore of clinical importance and has generated demand for a simple and rapid diagnostic test for carriage of HLA-B*5701. In this study, we describe the development of such a method based on allele-specific...

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Identifiers

PMID: 17559582
DOI: 10.1111/j.1399-0039.2007.00840.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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