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Article

A fluorescence-based sequence-specific primer PCR for the screening of HLA-B(*)57:01.

Electrophoresis - 1 Oct 2010

Giardina Emiliano, Stocchi Laura, Foti Cuzzola Valeria, Zampatti Stefania, Gambardella Stefano, Patrizi Maria Patrizia, Bramanti Placido, Pirazzoli Antonella, Novelli Giuseppe

Abstract excerpt

Abacavir (ABC) is an antiretroviral drug highly effective in the treatment of HIV, but its intake can cause severe hypersensitivity reaction (HSR). A strong association between HLA-B(*)57:01 and ABC HSRs was reported by several studies, which demonstrated that HLA-B(*)57:01 screening had a 100% negative predictive value and that it could accurately identify patients at high risk of ABC HSRs. We propose a new...

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Identifiers

PMID: 20925049
DOI: 10.1002/elps.201000283

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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