Article
Methylenetetrahydrofolate reductase genetic polymorphisms in patients with primary open-angle glaucoma.
Ophthalmic genetics - 1 Jun 2007
Zetterberg Madeleine, Tasa Gunnar, Palmér Mona Seibt, Juronen Erkki, Toover Egle, Blennow Kaj, Zetterberg Henrik
Abstract excerpt
PURPOSE: Hyperhomocysteinemia has been found in patients with primary open-angle glaucoma. The purpose of the present study was to determine if hyperhomocysteinemia-associated polymorphisms of the methylenetetrahydrofolate reductase gene (MTHFR) are overrepresented in primary open-angle glaucoma. METHODS: Patients with primary open-angle glaucoma (n = 243) and controls (n = 187) were analyzed for the MTHFR 677 C...
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