Article
Methylenetetrahydrofolate reductase gene polymorphisms c.677C/T and c.1298A/C are not associated with open angle glaucoma.
Molecular vision - 7 Jul 2006
Mabuchi Fumihiko, Tang Sa, Kashiwagi Kenji, Yamagata Zentaro, Iijima Hiroyuki, Tsukahara Shigeo
Abstract excerpt
PURPOSE: To assess whether or not the c.677C/T and c.1298A/C genetic polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) gene are associated with open angle glaucoma (OAG). METHODS: Genomic DNA was examined in a cohort of 131 Japanese patients with normal tension glaucoma (NTG), 133 patients with primary open angle glaucoma (POAG), and 106 control subjects. The mean age at the time of blood sampling...
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