Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

C677T polymorphism in the methylenetetrahydrofolate reductase gene is associated with primary closed angle glaucoma.

Molecular vision - 26 Mar 2008

Michael Shazia, Qamar Raheel, Akhtar Farah, Khan Wajid Ali, Ahmed Asifa

Abstract excerpt

PURPOSE: To determine whether or not there is an association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with disease in cohorts of primary open-angle glaucoma (POAG) and primary closed-angle glaucoma (PCAG) from Pakistan. METHODS: This was a prospective study consisting of 150 patients (90 POAG and 60 PCAG) and 70 control subjects. Genomic DNA was extracted from leukocytes of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Cytosine
Share to Glaucoma, Angle-Closure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glaucoma, Open-Angle

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Pakistan

Share to Polymorphism, Genetic

Share to Thymine

Source

Open in PubMed Open full text

Identifiers

PMID: 18385801
PMCID: PMC2277437

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

C677T polymorphism in the methylenetetrahydrofolate reductase gene is associated with primary closed angle glaucoma.PMID 18385801Read ↗

Association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with primary glaucoma in Saudi population.Semantic proximity Read ↗

MTHFR gene C677T and A1298C polymorphisms and homocysteine levels in primary open angle and primary closed angle glaucoma.Semantic proximity Read ↗

Association between MTHFR C677T polymorphism and primary open-angle glaucoma: a meta-analysis.Semantic proximity Read ↗

MTHFR C677T predisposes to POAG but not to PACG in a North Indian population: a case control study.Semantic proximity Read ↗

C677T variant in the methylentetrahydrofolate reductase gene is a genetic risk factor for primary open-angle glaucoma.Semantic proximity Read ↗

Association of known common genetic variants with primary open angle, primary angle closure, and pseudoexfoliation glaucoma in Pakistani cohorts.Semantic proximity Read ↗

Lack of association between the C677T single nucleotide polymorphism of the MTHFR gene and glaucoma in Iranian patients.Semantic proximity Read ↗

Methylenetetrahydrofolatereductase (MTHFR) 677C>T polymorphism and open angle glaucoma.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase genetic polymorphisms in patients with primary open-angle glaucoma.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene polymorphisms c.677C/T and c.1298A/C are not associated with open angle glaucoma.Semantic proximity Read ↗

Association of genetic variants with primary angle closure glaucoma in two different populations.Semantic proximity Read ↗

Association of eNOS polymorphisms with primary angle-closure glaucoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.