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Article

Homocysteine, B vitamins, methylenetetrahydrofolate reductase gene, and risk of primary open-angle glaucoma: a meta-analysis.

Ophthalmology - 1 Dec 2012

Xu Fan, Zhao Xin, Zeng Si-Ming, Li Li, Zhong Hai-Bin, Li Min

Abstract excerpt

BACKGROUND: To evaluate the association between plasma total homocysteine (tHcy) levels, serum folic acid, vitamin B(12) and vitamin B(6) levels, methylenetetrahydrofolate reductase (MTHFR) C677T genotype and risk of primary open-angle glaucoma (POAG). CLINICAL RELEVANCE: There are conflicting reports on the association of Hcy, folic acid, vitamin B(12), vitamin B(6), MTHFR, and risk of POAG. We conducted this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22902176
DOI: 10.1016/j.ophtha.2012.06.025

Genes

MTHFR

Variants

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