Article
Population-based case-control association studies.
Current protocols in human genetics - 1 Jan 2007
Hancock Dana B, Scott William K
Abstract excerpt
This unit provides an overview of the design and analysis of population-based case-control studies of genetic risk factors for complex disease. Considerations specific to genetic studies are emphasized. The unit reviews basic study designs, differentiating case-control studies from others, discusses selection of genetic markers for use in studies, introduces basic methods of analysis of case-control data, and...
Topics
- Case-Control Studies
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Methods
- Molecular Epidemiology
