Article
The emerging importance of genetics in epidemiologic research II. Issues in study design and gene mapping.
Annals of epidemiology - 1 Feb 1999
Ellsworth D L, Manolio T A
Abstract excerpt
PURPOSE: To provide a synthesis of current approaches to the discovery of genes associated with complex human diseases by examining the joint potential of traditional epidemiologic methods and current molecular techniques for gene discovery. METHODS: A discussion of optimal approaches for defining complex disease phenotypes in genetic epidemiology, ascertainment strategies for estimating genetic influences on...
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