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Article

High frequency of recombination-driven allelic diversity and temporal variation of Plasmodium falciparum msp1 in Tanzania.

The American journal of tropical medicine and hygiene - 1 Jun 2007

Tanabe Kazuyuki, Sakihama Naoko, Rooth Ingegerd, Björkman Anders, Färnert Anna

Abstract excerpt

A major mechanism for the generation allelic diversity in the Plasmodium falciparum msp1 gene is meiotic recombination in the Anopheles mosquito. The frequency of recombination events is dependent on the intensity of transmission. Herein we investigate the frequency of recombination-driven allelic diversity and temporal variation of msp1 in Rufiji, eastern coastal Tanzania, where malaria transmission is intense....

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PMID: 17556608

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