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Article

Recombination hotspots and population structure in Plasmodium falciparum.

PLoS biology - 1 Oct 2005

Mu Jianbing, Awadalla Philip, Duan Junhui, McGee Kate M, Joy Deirdre A, McVean Gilean A T, Su Xin-zhuan

Abstract excerpt

Understanding the influences of population structure, selection, and recombination on polymorphism and linkage disequilibrium (LD) is integral to mapping genes contributing to drug resistance or virulence in Plasmodium falciparum. The parasite's short generation time, coupled with a high cross-over rate, can cause rapid LD break-down. However, observations of low genetic variation have led to suggestions of...

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Identifiers

PMID: 16144426
DOI: 10.1371/journal.pbio.0030335
PMCID: PMC1201364

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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