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Article

Allelic dimorphism-associated restriction of recombination in Plasmodium falciparum msp1.

Gene - 1 Aug 2007

Tanabe Kazuyuki, Sakihama Naoko, Walliker David, Babiker Hamza, Abdel-Muhsin Abdel-Muhsin A, Bakote'e Bernard, Ohmae Hiroshi, Arisue Nobuko, Horii Toshihiro, Rooth Ingegerd, Färnert Anna, Björkman Anders, Ranford-Cartwright Lisa

Abstract excerpt

Allelic dimorphism is a characteristic feature of the Plasmodium falciparum msp1 gene encoding the merozoite surface protein 1, a strong malaria vaccine candidate. Meiotic recombination is a major mechanism for the generation of msp1 allelic diversity. Potential recombination sites have previously been mapped to specific regions within msp1 (a 5' 1-kb region and a 3' 0.4-kb region) with no evidence for...

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Identifiers

PMID: 17574779
DOI: 10.1016/j.gene.2007.04.033

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Source receipt: pubmed, retrieved 7 Sept 2026.

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