Article
Plasmodium falciparum: intragenic recombination and nonrandom associations between polymorphic domains of the precursor to the major merozoite surface antigens.
Experimental parasitology - 1 Nov 1991
Conway D J, Rosario V, Oduola A M, Salako L A, Greenwood B M, McBride J S
Abstract excerpt
Extensive allelic polymorphism in the Plasmodium falciparum major merozoite antigen precursor (MSP1/PMMSA) is partly due to intragenic recombination events within a short region near the 5' end of the gene. Newly described allelic sequences from this region of the gene are compared to those previously published, revealing additional sites of intragenic recombination. Epitopes recognised by monoclonal antibodies...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Antigens, Protozoan
- Base Sequence
- Chi-Square Distribution
- Epitopes
- Merozoite Surface Protein 1
- Molecular Sequence Data
- Plasmodium falciparum