Article
Limited allelic diversity of Plasmodium falciparum merozoite surface protein 1 gene from populations in the Solomon Islands.
The American journal of tropical medicine and hygiene - 1 Jan 2006
Sakihama Naoko, Ohmae Hiroshi, Bakote'e Bernard, Kawabata Masato, Hirayama Kenji, Tanabe Kazuyuki
Abstract excerpt
Meiotic recombination generates allelic diversity in the Plasmodium falciparum merozoite surface protein 1 (msp1) gene. In this study, we monitored recombination-based diversity of msp1 in Guadalcanal, the Solomon Islands, where malaria transmission is high. We identified 5' recombinant types, 3' sequence types, and msp1 haplotypes (unique associations of 5' recombinant types and 3' sequence types), and compared...
Topics
- Adolescent
- Adult
- Alleles
- Animals
- Child
- Genetic Variation
- Haplotypes
- Humans
- Infant
- Linkage Disequilibrium
- Malaria, Falciparum
- Melanesia
- Membrane Proteins
- Membrane Transport Proteins