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Article

Pericyte Rho GTPase mediates both pericyte contractile phenotype and capillary endothelial growth state.

The American journal of pathology - 1 Aug 2007

Kutcher Matthew E, Kolyada Alexey Y, Surks Howard K, Herman Ira M

Abstract excerpt

Pericytes regulate microvascular development and maturation through the control of endothelial cell motility, proliferation, and differentiation. The Rho GTPases have recently been described as key regulators of pericyte shape and contractile phenotype by signaling through the actin cytoskeleton in an isoactin-specific manner. In this report, we reveal that Rho GTPase-dependent signal transduction not only...

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Identifiers

PMID: 17556591
DOI: 10.2353/ajpath.2007.070102
PMCID: PMC1934521

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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