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Article

Calpain- and talin-dependent control of microvascular pericyte contractility and cellular stiffness.

Microvascular research - 1 Dec 2010

Kotecki Maciej, Zeiger Adam S, Van Vliet Krystyn J, Herman Ira M

Abstract excerpt

Pericytes surround capillary endothelial cells and exert contractile forces modulating microvascular tone and endothelial growth. We previously described pericyte contractile phenotype to be Rho GTPase- and α-smooth muscle actin (αSMA)-dependent. However, mechanisms mediating adhesion-dependent shape changes and contractile force transduction remain largely equivocal. We now report that the neutral cysteine...

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Identifiers

PMID: 20709086
DOI: 10.1016/j.mvr.2010.07.012
PMCID: PMC2981705

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AFM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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