Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miR-204-5p and Platelet Function Regulation: Insight into a Mechanism Mediated by CDC42 and GPIIbIIIa.

Thrombosis and haemostasis - 1 Sept 2021

Garcia Alix, Dunoyer-Geindre Sylvie, Nolli Séverine, Strassel Catherine, Reny Jean-Luc, Fontana Pierre

Abstract excerpt

BACKGROUND: Several platelet-derived microRNAs are associated with platelet reactivity (PR) and clinical outcome in cardiovascular patients. We previously showed an association between miR-204-5p and PR in stable cardiovascular patients, but data on functional mechanisms are lacking. AIMS: To validate miR-204-5p as a regulator of PR in platelet-like structures (PLS) derived from human megakaryocytes and to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Platelets
Share to cdc42 GTP-Binding Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Megakaryocytes

Share to MicroRNAs

Share to Phenotype

Share to Platelet Glycoprotein GPIIb-IIIa Complex

Share to Signal Transduction

Share to Thrombopoiesis

Source

Open in PubMed Open full text

Identifiers

PMID: 33940656
DOI: 10.1055/a-1497-9649
PMCID: PMC8421094

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miR-204-5p and Platelet Function Regulation: Insight into a Mechanism Mediated by CDC42 and GPIIbIIIa.PMID 33940656Read ↗

Megakaryocyte Cytoskeletal Proteins in Platelet Biogenesis and DiseasesSemantic proximity Read ↗

MicroRNAs in Platelet Physiology and FunctionSemantic proximity Read ↗

A circle of life: platelet and megakaryocyte cytoskeleton dynamics in health and disease.Semantic proximity Read ↗

Understanding megakaryocyte phenotypes and the impact on platelet biogenesis.Semantic proximity Read ↗

CRISPR-edited megakaryocytes for rapid screening of platelet gene functions.Semantic proximity Read ↗

The role of miRNAs in regulation of platelet activity and related diseases - a bioinformatic analysisSemantic proximity Read ↗

Regulation of the genetic code in megakaryocytes and platelets.Semantic proximity Read ↗

Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine plateletsSemantic proximity Read ↗

Insights into Regulatory Factors in Megakaryocyte Development and Function: Basic Mechanisms and Potential TargetsSemantic proximity Read ↗

MicroRNAs in platelet production and activationSemantic proximity Read ↗

Megakaryopoiesis and Platelet Biology: Roles of Transcription Factors and Emerging Clinical Implications.Semantic proximity Read ↗

Defining and Harnessing the Megakaryocyte/Platelet CheckpointSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.