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Article

A case control study of deep venous thrombosis in relation to factor V G1691A (Leiden) and A4070G (HR2 Haplotype) polymorphisms.

Experimental and molecular pathology - 1 Dec 2007

Bouaziz-Borgi Lobna, Nguyen Philipe, Hezard Nathalie, Musharrafieh Umayya, Almawi Wassim Y, Mahjoub Touhami

Abstract excerpt

Activated protein C resistance (APCR) is a significant risk factor for venous thromboembolism (VTE), with the factor V (FV) G1691A (Leiden) mutation accounting for the majority of inherited APCR cases. An additional FV polymorphism, A4074G (FV-HR2), reportedly increased VTE risk by some, but not all groups. We determined the prevalence of FV-Leiden and FV-HR2 SNPs in 126 patients with deep venous thrombosis...

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Identifiers

PMID: 17555744
DOI: 10.1016/j.yexmp.2007.04.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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