Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Factor V HR2 haplotype: a risk factor for venous thromboembolism in individuals with absence of Factor V Leiden.

Annals of hematology - 1 Dec 2008

Otrock Zaher K, Taher Ali T, Shamseddeen Wael A, Zaatari Ghazi, Bazarbachi Ali, Mahfouz Rami A

Abstract excerpt

Venous thromboembolism (VTE), including deep venous thrombosis (DVT) and pulmonary embolism (PE), occurs secondary to a number of hereditary and acquired disorders of hemostasis. A recently recognized polymorphism in Factor V (FV) gene H1299R (also named HR2) has been reported to be a possible risk factor for the development of VTE. The aim of this study is to evaluate the role of HR2 polymorphism in VTE in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Exons

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Factor V

Share to Haplotypes

Share to Lebanon

Share to Polymorphism, Single Nucleotide

Share to Prevalence

Share to Venous Thromboembolism

Source

Identifiers

PMID: 18654780
DOI: 10.1007/s00277-008-0543-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Factor V HR2 haplotype: a risk factor for venous thromboembolism in individuals with absence of Factor V Leiden.PMID 18654780Read ↗

Factor-V HR2 haplotype and thromboembolic disease.Semantic proximity Read ↗

Prevalence of factor V R2 (H1299R) polymorphism in the Lebanese population.Semantic proximity Read ↗

FV HR2 haplotype as additional inherited risk factor for deep vein thrombosis in individuals with a high-risk profile.Semantic proximity Read ↗

Association of factor V deficiency with factor V HR2.Semantic proximity Read ↗

Coinheritance of the HR2 haplotype in the factor V gene confers an increased risk of venous thromboembolism to carriers of factor V R506Q (factor V Leiden).Semantic proximity Read ↗

Coagulation factor V G allele and HR2 haplotype: factor V activity, activated protein C resistance and risk of venous thrombosis.Semantic proximity Read ↗

The HR2 haplotype of factor V: effects on factor V levels, normalized activated protein C sensitivity ratios and the risk of venous thrombosis.Semantic proximity Read ↗

Is homozygosity for the HR2 haplotype a risk factor for venous thromboembolism?Semantic proximity Read ↗

A prospective study of venous thromboembolism in relation to factor V Leiden and related factors.Semantic proximity Read ↗

A case control study of deep venous thrombosis in relation to factor V G1691A (Leiden) and A4070G (HR2 Haplotype) polymorphisms.Semantic proximity Read ↗

Increased factor VIII coagulant activity levels in male carriers of the factor V R2 polymorphism.Semantic proximity Read ↗

The factor V HR2 haplotype: prevalence and association of the A4070G and A6755G polymorphisms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.