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Article

A case control study on the contribution of factor V-Leiden, prothrombin G20210A, and MTHFR C677T mutations to the genetic susceptibility of deep venous thrombosis.

Journal of thrombosis and thrombolysis - 1 Jun 2005

Almawi Wassim Y, Tamim Hala, Kreidy Raghid, Timson Georgina, Rahal Elias, Nabulsi Malak, Finan Ramzi R, Irani-Hakime Noha

Abstract excerpt

BACKGROUND: Insofar as the inherited prothrombotic single nucleotide polymorphisms (SNPs) factor V G1691A (FV-Leiden), prothrombin (PRT) G20210A, and methylenetetrahydrofolate reductase (MTHFR), C677T are inherited risk factors of venous thromboembolism (VTE), the aim of this study was to determine the prevalence of single and combined SNPs in 198 patients with documented deep venous thrombosis (DVT), and 697...

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Source

Identifiers

PMID: 16082606
DOI: 10.1007/s11239-005-1313-x

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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A case control study on the contribution of factor V-Leiden, prothrombin G20210A, and MTHFR C677T mutations to the genetic susceptibility of deep venous thrombosis.PMID 16082606Read ↗

Risk of venous thromboembolism associated with single and combined effects of Factor V Leiden, Prothrombin 20210A and Methylenetethraydrofolate reductase C677T: a meta-analysis involving over 11,000 cases and 21,000 controls.Semantic proximity Read ↗

The genetics of venous thromboembolism. A meta-analysis involving approximately 120,000 cases and 180,000 controls.Semantic proximity Read ↗

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