Article
The Exon 3-Deleted Growth Hormone Receptor (d3GHR) Polymorphism - a Favorable Backdoor Mechanism for the GHR Function
2023-08-21
Abstract excerpt
Growth hormone (GH) is a peptide hormone that plays a crucial role in controlling growth, development, and lifespan. Molecular regulation of GH is accomplished via the GH receptor (GHR) gene, which is the main factor influencing human development and is essential to optimal functioning of the GH/IGF-I axis. Two GHR isoforms have been studied, according to the presence (flGHR) or absence (d3GHR) of exon 3. The d3GH...
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Identifiers and source
- Literature Corpus work
- 682ed5c4-3b10-5ab1-b307-17e4267b04ae
- DOI
- 10.20944/preprints202308.1470.v1
