Article
Acquisition of a natural resistance gene renders a clinical strain of methicillin‐resistant<i>Staphylococcus aureus</i>resistant to the synthetic antibiotic linezolid
14 May 2007
Abstract excerpt
Linezolid, which targets the ribosome, is a new synthetic antibiotic that is used for treatment of infections caused by Gram-positive pathogens. Clinical resistance to linezolid, so far, has been developing only slowly and has involved exclusively target site mutations. We have discovered that linezolid resistance in a methicillin-resistant Staphylococcus aureus hospital strain from Colombia is determined by the...
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