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Article

Emergence and Spread of <i>cfr</i> -Mediated Multiresistance in Staphylococci: An Interdisciplinary Challenge

1 Aug 2011

Abstract excerpt

In staphylococci, methylation of A2503 of 23S rRNA leads to resistance against several classes of antibiotics (oxazolidinones, phenicols, streptogramin compounds, lincosamidins and pleuromutilins). The corresponding resistance gene cfr is located on plasmid(s) and is transferable within and between staphylococcal species including Staphylococcus aureus. It first emerged in coagulase-negative staphylococci, later...

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PMID: 21861622
DOI: 10.2217/fmb.11.69

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