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Article

The N-terminus zinc finger domain of Xenopus SIP1 is important for neural induction, but not for suppression of Xbra expression.

The International journal of developmental biology - 1 Jan 2007

Nitta Kazuhiro R, Takahashi Shuji, Haramoto Yoshikazu, Fukuda Masakazu, Tanegashima Kousuke, Onuma Yasuko, Asashima Makoto

Abstract excerpt

Smad-interacting protein-1 (SIP1), also known as deltaEF2, ZEB2 and zfhx1b, is essential for the formation of the neural tube and the somites. Overexpression of Xenopus SIP1 causes ectopic neural induction via inhibition of bone morphogenetic protein (BMP) signaling and inhibition of Xbra expression. Here, we report the functional analyses of 4 domain-deletion mutants of XSIP1. Deletion of the N-terminus zinc...

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Identifiers

PMID: 17554684
DOI: 10.1387/ijdb.062252kn

Genes

ZEB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The N-terminus zinc finger domain of Xenopus SIP1 is important for neural induction, but not for suppression of Xbra expression.PMID 17554684Read ↗

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