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Article

Complementary expression pattern of Zfhx1 genes Sip1 and deltaEF1 in the mouse embryo and their genetic interaction revealed by compound mutants.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jul 2006

Miyoshi Tomoya, Maruhashi Mitsuji, Van De Putte Tom, Kondoh Hisato, Huylebroeck Danny, Higashi Yujiro

Abstract excerpt

In mouse embryos, the Zfhx1 transcription factor genes, Sip1 and deltaEF1, are expressed in complementary domains in many tissues. Their possible synergism in embryogenesis was investigated by comparing the phenotype of Sip1-/-;deltaEF1-/- double homozygotes with single homozygous embryos. Unexpectedly, in Sip1-/- embryos deltaEF1 was ectopically activated, suggesting a negative regulation of deltaEF1 expression...

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PMID: 16598713
DOI: 10.1002/dvdy.20799

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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