Article
Genetic variations in ABCA1/G1 associated with plasma lipid levels and risk of ischemic stroke.
Gene - 20 May 2022
Yang Shangdong, Jia Jing, Liu Yang, Li Zheng, Li Zhihao, Zhang Zhaojing, Zhou Baixue, Luan Yingying, Huang Yanyang, Peng Yue, Han Tianyi, Xu Yan, He Ying, Zheng Hong
Abstract excerpt
BACKGROUND: ATP binding cassette transporters ABCA1 and ABCG1 play a crucial role in cholesterol efflux and reverse cholesterol transport (RCT), thereby rendering ischemic stroke (IS) susceptibility. Variants of ABCA1/G1 have been implicated in etiology of IS. This study aimed to investigate the association between single-nucleotide polymorphisms (SNPs) of ABCA1/G1 with plasma lipid variability and the risk of IS...
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