Article
Interactive domains in the molecular chaperone human alphaB crystallin modulate microtubule assembly and disassembly.
PloS one - 6 Jun 2007
Ghosh Joy G, Houck Scott A, Clark John I
Abstract excerpt
BACKGROUND: Small heat shock proteins regulate microtubule assembly during cell proliferation and in response to stress through interactions that are poorly understood. METHODOLOGY: Novel functions for five interactive sequences in the small heat shock protein and molecular chaperone, human alphaB crystallin, were investigated in the assembly/disassembly of microtubules and aggregation of tubulin using synthetic...
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