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Article

Effect of amino acid mutations on intra-dimer tubulin-tubulin binding strength of microtubules.

Integrative biology : quantitative biosciences from nano to macro - 11 Dec 2017

Liu Ning, Pidaparti Ramana, Wang Xianqiao

Abstract excerpt

Energetic interactions inside αβ-tubulin dimers of a microtubule (MT) with atomic resolutions are of importance in determining the mechanical properties and structural stability of the MT as well as designing self-assembled functional structures from it. Here, we carry out several comprehensive atomistic simulations to investigate the interaction properties within αβ-tubulin dimers and effect of residue mutations...

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Identifiers

PMID: 29114690
DOI: 10.1039/c7ib00113d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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