Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A comparative study of molecular mutations in 381 patients with myelodysplastic syndrome and in 4130 patients with acute myeloid leukemia.

Haematologica - 1 Jun 2007

Bacher Ulrike, Haferlach Torsten, Kern Wolfgang, Haferlach Claudia, Schnittger Susanne

Abstract excerpt

BACKGROUND AND OBJECTIVES: The precise relationship between myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) is unclear and the role of molecular mutations in leukemic transformation in MDS is controversial. The aim of this study was to clarify the relationship between AML and MDS...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease
Share to fms-Like Tyrosine Kinase 3
Share to Histone-Lysine N-Methyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid

Share to Myelodysplastic Syndromes

Share to Myeloid-Lymphoid Leukemia Protein

Share to Proto-Oncogene Proteins c-kit

Share to ras Proteins

Source

Identifiers

PMID: 17550846
DOI: 10.3324/haematol.10869

Genes

FLT3
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17550846-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A comparative study of molecular mutations in 381 patients with myelodysplastic syndrome and in 4130 patients with acute myeloid leukemia.PMID 17550846Read ↗

The Genetic Landscape of Myelodysplastic Neoplasm Progression to Acute Myeloid Leukemia.Semantic proximity Read ↗

[Risk factors for leukemia transformation in patients with myelodysplastic syndromes].Semantic proximity Read ↗

[Molecular features and prognostic value of RAS mutations in patients with myelodysplastic syndromes].Semantic proximity Read ↗

Interrogation of molecular profiles can help in differentiating between MDS and AML with MDS-related changes.Semantic proximity Read ↗

Acute Myeloid Leukemia with Myelodysplasia-Related Gene MutationsSemantic proximity Read ↗

Genetic Factors in Acute Myeloid Leukemia With Myelodysplasia-Related Changes.Semantic proximity Read ↗

Targeted resequencing analysis of 31 genes commonly mutated in myeloid disorders in serial samples from myelodysplastic syndrome patients showing disease progressionSemantic proximity Read ↗

[Mutation analysis of 77 patients with normal-karyotype myelodysplastic syndrome].Semantic proximity Read ↗

Sequential acquisition of mutations in myelodysplastic syndromes.Semantic proximity Read ↗

Poor prognostic implications of myelodysplasia-related mutations in both older and younger patients with de novo AML.Semantic proximity Read ↗

Distinct Mutation Landscapes Between Acute Myeloid Leukemia With Myelodysplasia-Related Changes and De Novo Acute Myeloid Leukemia.Semantic proximity Read ↗

Implications of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome (MDS): future molecular therapeutic directions for MDS.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.