Article
[Molecular features and prognostic value of RAS mutations in patients with myelodysplastic syndromes].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 14 Sept 2020
Huang H J, Li B, Qin T J, Xu Z F, Hu N B, Pan L J, Qu S Q, Liu D, Zhang Y D, Xiao Z J
Abstract excerpt
Objective: To explore the molecular features and prognostic value of RAS mutations in patients with myelodysplastic syndromes (MDS) . Methods: 112-gene targeted sequencing was conducted to detect RAS mutations in 776 patients with newly diagnosed primary MDS from December 2011 to December 2018. The mutual exclusivity and co-occurrence in gene mutations and clonal architecture were explored. Moreover, the...
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