Article
Genetic Factors in Acute Myeloid Leukemia With Myelodysplasia-Related Changes.
American journal of clinical pathology - 15 Apr 2020
Fang Hong, He Rong, Chiu April, Viswanatha David S, Ketterling Rhett P, Patnaik Mrinal S, Reichard Kaaren K
Abstract excerpt
OBJECTIVES: Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) is a heterogeneous category with a broad range of underlying genetic abnormalities. We investigated the significance of genetic factors in a large series of AML-MRC cases. METHODS: The morphologic findings, genetic data, and patient outcomes were assessed in 186 AML-MRC cases. RESULTS: The median overall survival (OS) was dismal in...
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