HaploBuild: an algorithm to construct non-contiguous associated haplotypes in family based genetic studies.

doi:10.1093/bioinformatics/btm316

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Article

HaploBuild: an algorithm to construct non-contiguous associated haplotypes in family based genetic studies.

Bioinformatics (Oxford, England) - 15 Aug 2007

Laramie Jason M, Wilk Jemma B, DeStefano Anita L, Myers Richard H

Abstract excerpt

UNLABELLED: We have created a program that searches densely genotyped regions for associated non-contiguous haplotypes using a standard family based haplotype association test. This program was designed to expand upon the 'sliding window' methodologies commonly used for haplotype construction by allowing the association of subsets of single nucleotide polymorphisms (SNPs) to drive the construction of the...

Topics

Algorithms
Biological Evolution
Contig Mapping
Family
Genetic Linkage
Genetic Variation
Genetics, Population
Haplotypes
Pedigree
Software

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Identifiers

PMID: 17586827
DOI: 10.1093/bioinformatics/btm316
PMCID: PMC2665175

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