Article
IL-10 Underlies Distinct Susceptibility of BALB/c and C57BL/6 Mice to <i>Mycobacterium avium</i> Infection and Influences Efficacy of Antibiotic Therapy
1 Jun 2007
Abstract excerpt
Increased production of IL-10 has been frequently associated with augmented susceptibility to infection. However, the correlation between IL-10 activity and susceptibility to mycobacterial infection is still uncertain. Although studies using transgenic mice overexpressing IL-10 consistently showed an increased susceptibility to mycobacterial infection, experimental approaches in which IL-10 activity was reduced...
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