Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Host genetic background affects regulatory T-cell activity that influences the magnitude of cellular immune response against Mycobacterium tuberculosis.

Immunology and cell biology - 1 May 2011

Paula Marina Oliveira, Fonseca Denise Morais, Wowk Pryscilla Fanini, Gembre Ana Flávia, Fedatto Paola Fernanda, Sérgio Cássia Alves, Silva Célio Lopes, Bonato Vânia Luiza Deperon

Abstract excerpt

Using two mouse strains with different abilities to generate interferon (IFN)-γ production after Mycobacterium tuberculosis infection, we tested the hypothesis that the frequency and activity of regulatory T (Treg) cells are influenced by genetic background. Our results demonstrated that the supp...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Load
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD8-Positive T-Lymphocytes

Share to Immunity, Cellular

Share to Interleukin-17

Share to Spleen

Share to T-Lymphocytes, Regulatory

Share to Tuberculosis

Source

Identifiers

PMID: 20956987
DOI: 10.1038/icb.2010.116

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20956987-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Host genetic background affects regulatory T-cell activity that influences the magnitude of cellular immune response against Mycobacterium tuberculosis.PMID 20956987Read ↗

BALB/c mice have more CD4+CD25+ T regulatory cells and show greater susceptibility to suppression of their CD4+CD25- responder T cells than C57BL/6 mice.Semantic proximity Read ↗

Regulation of Immunity to TuberculosisSemantic proximity Read ↗

Aberrant adaptive immune response underlies genetic susceptibility to tuberculosis.Semantic proximity Read ↗

Elucidating different pattern of immunoregulation in BALB/c and C57BL/6 mice and their F1 progeny.Semantic proximity Read ↗

Anti-CD25 treatment depletes Treg cells and decreases disease severity in susceptible and resistant mice infected with Paracoccidioides brasiliensis.Semantic proximity Read ↗

Regulatory CD4+CD25+ T Cells Dampen Inflammatory Disease in Murine Mycoplasma Pneumonia and Promote IL-17 and IFN-γ Responses.Semantic proximity Read ↗

RORγt+ Treg to Th17 ratios correlate with susceptibility to Giardia infection.Semantic proximity Read ↗

CD11c(+) CD103(+) cells of Mycobacterium tuberculosis-infected C57BL/6 but not of BALB/c mice induce a high frequency of interferon-γ- or interleukin-17-producing CD4(+) cells.Semantic proximity Read ↗

Levels of dendritic cell populations and regulatory T cells vary significantly between two commonly used mouse strains.Semantic proximity Read ↗

Differences in the ability to generate type 1 T helper cells need not determine differences in the ability to resist Mycobacterium tuberculosis infection among mouse strains.Semantic proximity Read ↗

IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo.Semantic proximity Read ↗

Capacity of lung stroma to educate dendritic cells inhibiting mycobacteria-specific T-cell response depends upon genetic susceptibility to tuberculosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.