Article
Sex-dependent susceptibility to Listeria monocytogenes infection is mediated by differential interleukin-10 production.
Infection and immunity - 1 Sept 2005
Pasche Bastian, Kalaydjiev Svetoslav, Franz Tobias J, Kremmer Elisabeth, Gailus-Durner Valérie, Fuchs Helmut, Hrabé de Angelis Martin, Lengeling Andreas, Busch Dirk H
Abstract excerpt
It is well documented that sex-dependent factors affect susceptibility to infection, with most mouse models demonstrating higher resistance in females. We made the unexpected observation that infection with the intracellular bacterium Listeria monocytogenes showed an opposite pattern in several commonly used inbred mouse strains: female C57BL/6J, BALB/c, C3H/HeN, and CBA/J mice were significantly more susceptible...
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