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Article

The Trypanosoma brucei DNA polymerase alpha core subunit gene is developmentally regulated and linked to a constitutively expressed open reading frame.

Nucleic acids research - 11 Dec 1991

Leegwater P A, Strating M, Murphy N B, Kooy R F, van der Vliet P C, Overdulve J P

Abstract excerpt

As an initial step towards the characterization of replicative DNA polymerases of trypanosomes, we have cloned, sequenced and examined the expression of the Trypanosoma (Trypanozoon) brucei brucei gene that encodes the DNA polymerase alpha catalytic core (pol alpha). The protein sequence contains the six conserved regions that have been recognized previously in eukaryotic and viral replicative DNA polymerases. In...

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Identifiers

PMID: 1754381
DOI: 10.1093/nar/19.23.6441
PMCID: PMC329194

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