Article

Beyond the transcript: chromatin implications in trans-splicing in Trypanosomatids

2025-07-11

Abstract excerpt

Trypanosoma cruzi, Trypanosoma brucei and Leishmania major , usually known as TriTryps, are the causal agents of animal and human sickness, and are characterized by having complex life cycles, alternating between a mammalian host and an insect vector. Their genes are organized in long transcriptional units that give rise to polycistronic transcripts which maturate into mRNA by a process known as trans-splicing. A...

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Literature Corpus work: ec525a6b-c754-54ea-becf-40e45d88a552
DOI: 10.1101/2025.07.08.663533

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