Article
Essential role of lysyl oxidases in notochord development.
Developmental biology - 15 Jul 2007
Gansner John M, Mendelsohn Bryce A, Hultman Keith A, Johnson Stephen L, Gitlin Jonathan D
Abstract excerpt
Recent studies reveal a critical role for copper in the development of the zebrafish notochord, suggesting that specific cuproenzymes are required for the structural integrity of the notochord sheath. We now demonstrate that beta-aminopropionitrile, a known inhibitor of the copper-dependent lysyl...
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