Article
Mutations affecting development of the notochord in zebrafish.
Development (Cambridge, England) - 1 Dec 1996
Stemple D L, Solnica-Krezel L, Zwartkruis F, Neuhauss S C, Schier A F, Malicki J, Stainier D Y, Abdelilah S, Rangini Z, Mountcastle-Shah E, Driever W
Abstract excerpt
The notochord is critical for the normal development of vertebrate embryos. It serves both as the major skeletal element of the embryo and as a signaling source for the establishment of pattern within the neurectoderm, the paraxial mesoderm and other tissues. In a large-scale systematic screen of mutations affecting embryogenesis in zebrafish we identified 65 mutations that fall into 29 complementation groups,...
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