Article
Impact of DNA repair, folate and glutathione gene polymorphisms on risk of non small cell lung cancer.
Pathology, research and practice - 1 Jan 2018
Pérez-Ramírez Cristina, Cañadas-Garre Marisa, Alnatsha Ahmed, Villar Eduardo, Delgado Juan Ramón, Calleja-Hernández Miguel Ángel, Faus-Dáder María José
Abstract excerpt
Lung cancer, particularly non-small cell lung cancer (NSCLC) subtype, is the leading cause of cancer-related death related worldwide. Numerous gene polymorphisms in DNA repair, folate and glutathione pathways have been associated with susceptibility of NSCLC. We conducted this study to evaluate the effects of ERCC1, ERCC2, ERCC5, XRCC1, XRCC3, MTHFR, MTR, MTHFD1, SLC19A1 and GSTP1 gene polymorphisms on risk of...
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