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Article

Transport of truncated rhodopsin and its effects on rod function and degeneration.

Investigative ophthalmology & visual science - 1 Jun 2007

Lee Edwin S, Flannery John G

Abstract excerpt

PURPOSE: Most transgenic animal models of retinal degeneration caused by rhodopsin mutations express the rhodopsin transgene on a wild-type (WT) genetic background. Previous studies have demonstrated that one mechanism of retinal degeneration is rhodopsin overexpression. To study the effect of C-terminal truncation of rhodopsin without the confounding factors of overexpression, several lines of transgenic mice...

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Source

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Identifiers

PMID: 17525223
DOI: 10.1167/iovs.06-0035
PMCID: PMC2570206

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ERG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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