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Article

Protein kinase Czeta abrogates the proapoptotic function of Bax through phosphorylation.

The Journal of biological chemistry - 20 Jul 2007

Xin Meiguo, Gao Fengqin, May W Stratford, Flagg Tammy, Deng Xingming

Abstract excerpt

Protein kinase Czeta (PKCzeta) is an atypical PKC isoform that plays an important role in supporting cell survival but the mechanism(s) involved is not fully understood. Bax is a major member of the Bcl-2 family that is required for apoptotic cell death. Because Bax is extensively co-expressed with PKCzeta in both small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) cells, it is possible that Bax...

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Source

Identifiers

PMID: 17525161
DOI: 10.1074/jbc.M701613200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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