Article
Protein kinase Czeta abrogates the proapoptotic function of Bax through phosphorylation.
The Journal of biological chemistry - 20 Jul 2007
Xin Meiguo, Gao Fengqin, May W Stratford, Flagg Tammy, Deng Xingming
Abstract excerpt
Protein kinase Czeta (PKCzeta) is an atypical PKC isoform that plays an important role in supporting cell survival but the mechanism(s) involved is not fully understood. Bax is a major member of the Bcl-2 family that is required for apoptotic cell death. Because Bax is extensively co-expressed wi...
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