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Article

Atypical protein kinase C zeta as a target for chemosensitization of tumor cells.

Cancer research - 15 Mar 2002

Filomenko Rodolphe, Poirson-Bichat Florence, Billerey Claire, Belon Jean-Paul, Garrido Carmen, Solary Eric, Bettaieb Ali

Abstract excerpt

Exposure of tumor cells to cytotoxic agents simultaneously activates a variety of intracellular signaling pathways. Some of these pathways involve enzymes from the protein kinase C (PKC) family of serine/threonine kinases. This family includes isoenzymes that negatively influence cell death, whereas other demonstrate an opposite effect. The present study analyzes the role of the zeta atypical PKC isoform in tumor...

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PMID: 11912160

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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