Article
Analyses of SUM1-1-mediated long-range repression.
Genetics - 1 Jan 2006
Valenzuela Lourdes, Gangadharan Sunil, Kamakaka Rohinton T
Abstract excerpt
In Saccharomyces cerevisiae, local repression is promoter specific and localized to a small region on the DNA, while silencing is promoter nonspecific, encompasses large domains of chromatin, and is stably inherited for multiple generations. Sum1p is a local repressor protein that mediates repression of meiosis-specific genes in mitotic cells while the Sir proteins are long-range repressors that stably silence...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
