Article
Assessment of methylation events during colorectal tumor progression by absolute quantitative analysis of methylated alleles.
Molecular cancer research : MCR - 1 May 2007
de Maat Michiel F G, Umetani Naoyuki, Sunami Eiji, Turner Roderick R, Hoon Dave S B
Abstract excerpt
To date, the epigenetic events involved in the progression of colorectal cancer are not well described. To study, in detail, methylation during colorectal cancer development in high-risk adenomas, we developed an assay combining in situ (on-slide) sodium bisulfite modification (SBM) of paraffin-e...
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