Article
TGFBR1*6A and cancer risk: a meta-analysis of seven case-control studies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Sept 2003
Kaklamani Virginia G, Hou Nanjiang, Bian Yiansong, Reich Jennifer, Offit Kenneth, Michel Loren S, Rubinstein W S, Rademaker Alfred, Pasche Boris
Abstract excerpt
PURPOSE: TGFBR1*6A is a hypomorphic polymorphic allele of the type I transforming growth factor beta receptor (TGFBR1). TGFBR1*6A is a candidate tumor susceptibility allele that has been associated with an increased incidence of various types of cancer. This study was undertaken to analyze all published case-control studies on TGFBR1*6A and cancer and determine whether TGFBR1*6A is associated with cancer....
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