Article
Human lung-derived mature mast cells cultured alone or with mouse 3T3 fibroblasts maintain an ultrastructural phenotype different from that of human mast cells that develop from human cord blood cells cultured with 3T3 fibroblasts.
The American journal of pathology - 1 Dec 1991
Dvorak A M, Furitsu T, Estrella P, Ishizaka T
Abstract excerpt
Culture systems designed to maintain or develop human mast cells have proved difficult, yet these systems would provide valuable resources for future investigations of human mast cell biology. Cocultures of either isolated mature human lung mast cells (Levi-Schaffer et al., J Immunol 1987, 139:494-500) or human cord blood mononuclear cells (Furitsu, Proc Natl Acad Sci USA 1989, 86:10039-10043) with 3T3 embryonic...
Topics
- 3T3 Cells
- Animals
- Cells, Cultured
- Cellular Senescence
- Cytological Techniques
- Fetal Blood
- Humans
- Lung
- Mast Cells
- Mice
- Phenotype