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Article

Mast cell lineage development and phenotypic regulation.

Leukemia research - 1 Jul 2001

Austen K F, Boyce J A

Abstract excerpt

Three cornerstones of mast cell development are an absolute dependence on the presence of stem cell factor, T-cell-independent and T-cell-dependent tissue mast cell populations derived from a single lineage, and a diversity of phenotypes for mature tissue mast cells as defined by immunohistochemical and biochemical properties. The in vivo biology of the mast cell in the mouse has been deduced through the...

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PMID: 11377675
DOI: 10.1016/s0145-2126(01)00030-3

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