Article
Stimulation of partial development of human mast cells by supernatant fluid from mouse fibroblast cultures.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jul 1994
Dvorak A M, Mitsui H, Ishizaka T
Abstract excerpt
Fibroblasts have been implicated as culture-competent cells for the mast cell lineage in several species. In man, fibroblast monolayers sustain the ultrastructural phenotype and function of isolated human lung mast cells and permit the differentiation and full maturation of human mast cells from their agranular precursors in cord blood cells. We examined whether development and maturation of the mast cell lineage...
Topics
- Animals
- Biological Factors
- Cell Differentiation
- Cell Division
- Cell Line
- Cells, Cultured
- Culture Media
- Fetal Blood
- Fibroblasts
- Humans
- Mast Cells
