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Article

Structure of the NMDA receptor channel M2 segment inferred from the accessibility of substituted cysteines.

Neuron - 1 Aug 1996

Kuner T, Wollmuth L P, Karlin A, Seeburg P H, Sakmann B

Abstract excerpt

The structure of the NMDA receptor channel M2 segment was investigated by probing the extracellular and cytoplasmic faces of cysteine-substituted NR1-NR2C channels with charged sulfhydryl-specific reagents. The pattern of accessible positions suggests that the M2 segment forms a channel-lining lo...

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PMID: 8780657
DOI: 10.1016/s0896-6273(00)80165-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8780657-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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